Cosmid: Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into e. Coli: this permits cloning of larger dna fragments (up to 45 kb) than can be introduced into bacterial hosts in plasmid vectors.

 

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Cosmid: Artificially constructed cloning vector containing the cos gene of phage lambda. Cosmids can be packaged in lambda phage particles for infection into e. Coli: this permits cloning of larger . . . View Full Definition

Yeast Artificial Chromosome (YAC): A vector used to clone dna fragments (up to 400 kb): it is constructed from the telomeric, centromeric, and replication origin sequences needed for replication in yeast cells. Compare clonin . . . View Full Definition

Cloning Vector: Dna molecule originating from a virus, a plasmid, or the cell of a higher organism into which another dna fragment of appropriate size can be integrated without loss of the vectors capacity . . . View Full Definition

Arrayed Library: Individual primary recombinant clones (hosted in phage, cosmid, yac, or other vector) that are placed in two-dimensional arrays in microtiter dishes. Each primary clone can be identified by . . . View Full Definition